RFdiffusion + AF2 initial guess v1
Standard cuts from the Baker lab's dl_binder_design line.
| Criteria | Condition | When not measured | Remarks |
|---|---|---|---|
PAE (interface, raw) metrics.pae_interaction |
< 10 Å | Skip | Raw PAE (Å). A different physical quantity from BindCraft's normalized i_pAE. |
Binder pLDDT metrics.plddt_binder |
> 80.0 | Skip |
Why the default is Skip: it is routine for an imported CSV to be missing a particular metric. Cutting every design over a metric nobody measured would make this tool useless. Skipped criteria show up in the results as "Not measured".
Application history
| Version | Campaigns | Result | Bottleneck criterion | Time |
|---|---|---|---|---|
| v1 | pd-l1/campaign/pdl1-r1 | 24 → 6 | Binder pLDDT 17 cut PAE (interface, raw) 16 cut | 2026-08-26 18:13:31 |
| v1 | pd-l1/캠페인/pdl1-r1 | 24 → 6 | 바인더 pLDDT 17 cut PAE (계면, 원시) 16 cut | 2026-08-26 14:12:40 |