pd-l1
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campaign
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pdl1-r1
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design
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demo-pdl1-010
DEMO-PDL1-010 Design data
This design is an imported data row — not yet a wiki page. There is no body, history, or backlinks, but you can sort and filter it quickly in the table.
Demo data — The sequence and metrics are synthetic values for on-screen demos. Not a real design result.
Sequence 54 aa
1 MAEEAKKTLE DAKKTLGNGT MEELKKNLEE AKSTQWGTPS AEELKKRLEE NKKL
Properties
Molecular weight 6133.98 Theoretical pI 6.89 Net charge at pH 7.4 -0.06 GRAVY -1.348 Hydrophobic fraction 0.2778 Extinction coefficient (A280) 5500 Cys count 0
Developability warnings
Deamidation @18 NG — Asn deamidation — charge variant on storageOxidation @1 M — Met oxidationOxidation @21 M — Met oxidationOxidation @36 W — Trp oxidation — can drive aggregationN-glycan sequon @18 NGT — 진핵 발현 시 당사슬이 붙는다 — 대장균이면 무해
Metrics
plddt_complex 0.8374 plddt_binder 0.7946 i_ptm 0.5279 ptm 0.8367 i_pae_norm 0.4942 pae_interaction 18.6379 hbonds_interface 1 unsat_hbonds 8 binder_surface_hydrophobicity 0.3439 binder_rmsd 2.1303 ddg -29.8 sasa_buried 1633 shape_complementarity 0.533
Filters
bindcraft_default v1
Fail (4/8)
rfdiff_af2ig v1
Fail (0/2)