pd-l1
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pdl1-r1
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design
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demo-pdl1-011
DEMO-PDL1-011 Design data
This design is an imported data row — not yet a wiki page. There is no body, history, or backlinks, but you can sort and filter it quickly in the table.
Demo data — The sequence and metrics are synthetic values for on-screen demos. Not a real design result.
Sequence 56 aa
1 MALELKKLLE EAKKLLEAAY GNGTAEEWKK LLEEMKSLLK GNGTAYELKK QLMEAK
Properties
Molecular weight 6354.53 Theoretical pI 8.97 Net charge at pH 7.4 0.94 GRAVY -0.568 Hydrophobic fraction 0.4464 Extinction coefficient (A280) 8480 Cys count 0
Developability warnings
Deamidation @22 NG — Asn deamidation — charge variant on storageDeamidation @42 NG — Asn deamidation — charge variant on storageOxidation @1 M — Met oxidationOxidation @28 W — Trp oxidation — can drive aggregationOxidation @35 M — Met oxidationOxidation @53 M — Met oxidationN-glycan sequon @22 NGT — 진핵 발현 시 당사슬이 붙는다 — 대장균이면 무해N-glycan sequon @42 NGT — 진핵 발현 시 당사슬이 붙는다 — 대장균이면 무해
Metrics
plddt_complex 0.6328 plddt_binder 0.7388 i_ptm 0.3613 ptm 0.7024 i_pae_norm 0.4857 pae_interaction 17.7885 hbonds_interface 2 unsat_hbonds 4 binder_surface_hydrophobicity 0.3049 binder_rmsd 2.7427 ddg -38.8 sasa_buried 798
Filters
bindcraft_default v1
Fail (2/7)
rfdiff_af2ig v1
Fail (0/2)