pd-l1
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campaign
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pdl1-r1
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design
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demo-pdl1-017
DEMO-PDL1-017 Design data
This design is an imported data row — not yet a wiki page. There is no body, history, or backlinks, but you can sort and filter it quickly in the table.
Demo data — The sequence and metrics are synthetic values for on-screen demos. Not a real design result.
Sequence 57 aa
1 MAEELKRLLK EAKKLLEEAI GNGTAEVWKK LLEEAKKLLS EIKSGGPAEE LKKLWEM
Properties
Molecular weight 6479.68 Theoretical pI 6.89 Net charge at pH 7.4 -0.06 GRAVY -0.537 Hydrophobic fraction 0.4211 Extinction coefficient (A280) 11000 Cys count 0
Developability warnings
Deamidation @22 NG — Asn deamidation — charge variant on storageOxidation @1 M — Met oxidationOxidation @28 W — Trp oxidation — can drive aggregationOxidation @55 W — Trp oxidation — can drive aggregationOxidation @57 M — Met oxidationN-glycan sequon @22 NGT — 진핵 발현 시 당사슬이 붙는다 — 대장균이면 무해
Metrics
plddt_complex 0.667 plddt_binder 0.7839 i_ptm 0.523 ptm 0.7503 i_pae_norm 0.4757 pae_interaction 11.1673 hbonds_interface 4 unsat_hbonds 8 binder_surface_hydrophobicity 0.3121 binder_rmsd 1.3304 ddg -26.1 sasa_buried 827
Filters
bindcraft_default v1
Fail (4/7)
rfdiff_af2ig v1
Fail (0/2)