DEMO-PDL1-023 Design data

Sequence 58 aa

    1  MAEELKKLLE WLKVLKEGSG SAEELKKLVE EAKKQAEEAT GTPSEEFMKK LLEEAVKY

Properties

Molecular weight6596.65
Theoretical pI4.68
Net charge at pH 7.4-3.06
GRAVY-0.69
Hydrophobic fraction0.3966
Extinction coefficient (A280)6990
Cys count0

Developability warnings

  • Oxidation @1 M — Met oxidation
  • Oxidation @11 W — Trp oxidation — can drive aggregation
  • Oxidation @48 M — Met oxidation