pd-l1
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campaign
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pdl1-r1
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design
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demo-pdl1-024
DEMO-PDL1-024 Design data
This design is an imported data row — not yet a wiki page. There is no body, history, or backlinks, but you can sort and filter it quickly in the table.
Demo data — The sequence and metrics are synthetic values for on-screen demos. Not a real design result.
Sequence 58 aa
1 MMFELKKLLA EAKKLGNGTQ EELKKLLQEN KKLLIPDGSA EDLMKLLEEA KKALRKAK
Properties
Molecular weight 6595.95 Theoretical pI 10.28 Net charge at pH 7.4 3.94 GRAVY -0.609 Hydrophobic fraction 0.4138 Extinction coefficient (A280) 0 Cys count 0
Developability warnings
Deamidation @17 NG — Asn deamidation — charge variant on storageIsomerisation @37 DG — Asp isomerisation — can cost bindingOxidation @1 M — Met oxidationOxidation @2 M — Met oxidationOxidation @44 M — Met oxidationN-glycan sequon @17 NGT — 진핵 발현 시 당사슬이 붙는다 — 대장균이면 무해
Metrics
plddt_complex 0.6752 plddt_binder 0.7353 i_ptm 0.4698 ptm 0.8424 i_pae_norm 0.5702 pae_interaction 19.8209 hbonds_interface 0 unsat_hbonds 8 binder_surface_hydrophobicity 0.4272 binder_rmsd 5.3765 ddg -35.4 sasa_buried 1069 shape_complementarity 0.6589
Filters
bindcraft_default v1
Fail (1/8)
rfdiff_af2ig v1
Fail (0/2)