PD-L1
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PDL1-R1
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Design
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DEMO-PDL1-007
DEMO-PDL1-007 Design data
This design is an imported data row — not yet a wiki page. There is no body, history, or backlinks, but you can sort and filter it quickly in the table.
Demo data — The sequence and metrics are synthetic values for on-screen demos. Not a real design result.
Sequence 55 aa
1 MAEWLKKALE EAKKLLEESG GPAEELKKLL REAQKRGNGT AEYLKKLLME AKKLL
Properties
Molecular weight 6254.44 Theoretical pI 10.02 Net charge at pH 7.4 2.94 GRAVY -0.705 Hydrophobic fraction 0.4182 Extinction coefficient (A280) 6990 Cys count 0
Developability warnings
Deamidation @38 NG — Asn deamidation — charge variant on storageOxidation @1 M — Met oxidationOxidation @4 W — Trp oxidation — can drive aggregationOxidation @49 M — Met oxidationN-glycan sequon @38 NGT — 진핵 발현 시 당사슬이 붙는다 — 대장균이면 무해
Metrics
plddt_complex 0.6719 plddt_binder 0.6978 i_ptm 0.2962 ptm 0.7212 i_pae_norm 0.2416 pae_interaction 11.5757 hbonds_interface 2 unsat_hbonds 8 binder_surface_hydrophobicity 0.438 binder_rmsd 2.2652 ddg -17.3 sasa_buried 1565 shape_complementarity 0.5197
Filters
bindcraft_default v1
Fail (2/8)
rfdiff_af2ig v1
Fail (0/2)