PD-L1
/
Campaign
/
PDL1-R1
/
Design
/
DEMO-PDL1-008
DEMO-PDL1-008 Design data
This design is an imported data row — not yet a wiki page. There is no body, history, or backlinks, but you can sort and filter it quickly in the table.
Demo data — The sequence and metrics are synthetic values for on-screen demos. Not a real design result.
Sequence 63 aa
1 MALVRKKLLE EAKKLLEWAK GNGTKFESKK LLEEAKKLLE EAPDGSAEEL RKLLEWIKKL
61 KEE
Properties
Molecular weight 7336.69 Theoretical pI 9.72 Net charge at pH 7.4 1.94 GRAVY -0.784 Hydrophobic fraction 0.3968 Extinction coefficient (A280) 11000 Cys count 0
Developability warnings
Deamidation @22 NG — Asn deamidation — charge variant on storageIsomerisation @44 DG — Asp isomerisation — can cost bindingOxidation @1 M — Met oxidationOxidation @18 W — Trp oxidation — can drive aggregationOxidation @56 W — Trp oxidation — can drive aggregationN-glycan sequon @22 NGT — 진핵 발현 시 당사슬이 붙는다 — 대장균이면 무해Hydrophobic patch @1 MALV — 연속 소수성 4잔기 — 응집·비특이 결합 위험
Metrics
plddt_complex 0.8135 plddt_binder 0.728 i_ptm 0.4896 ptm 0.7025 i_pae_norm 0.3998 pae_interaction 14.975 hbonds_interface 4 unsat_hbonds 9 binder_surface_hydrophobicity 0.2797 binder_rmsd 3.3931 ddg -13.7 sasa_buried 1627
Filters
bindcraft_default v1
Fail (4/7)
rfdiff_af2ig v1
Fail (0/2)