PD-L1
/
Campaign
/
PDL1-R1
/
Design
/
DEMO-PDL1-012
DEMO-PDL1-012 Design data
This design is an imported data row — not yet a wiki page. There is no body, history, or backlinks, but you can sort and filter it quickly in the table.
Demo data — The sequence and metrics are synthetic values for on-screen demos. Not a real design result.
Sequence 59 aa
1 MAWELKKLLV QLKKLLEEAK SGGPAKALKK LLDEAMRTLE GNGTDMEIKV LLEEAKKEL
Properties
Molecular weight 6621.94 Theoretical pI 9.13 Net charge at pH 7.4 0.94 GRAVY -0.346 Hydrophobic fraction 0.4407 Extinction coefficient (A280) 5500 Cys count 0
Developability warnings
Deamidation @42 NG — Asn deamidation — charge variant on storageOxidation @1 M — Met oxidationOxidation @3 W — Trp oxidation — can drive aggregationOxidation @36 M — Met oxidationOxidation @46 M — Met oxidationN-glycan sequon @42 NGT — 진핵 발현 시 당사슬이 붙는다 — 대장균이면 무해
Metrics
plddt_complex 0.6613 plddt_binder 0.7588 i_ptm 0.4326 ptm 0.8554 i_pae_norm 0.5533 pae_interaction 8.5306 hbonds_interface 6 unsat_hbonds 2 binder_surface_hydrophobicity 0.3918 binder_rmsd 1.7632 ddg -18.9 sasa_buried 1181 shape_complementarity 0.5209
Filters
bindcraft_default v1
Fail (3/8)
rfdiff_af2ig v1
Fail (1/2)