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DEMO-PDL1-015 Design data

Sequence 57 aa

    1  MALELKKLTE EAKKLLEESS GGPAEELKKL REELKKLPDG SQRELQKLLE EAKKLLE

Properties

Molecular weight6517.63
Theoretical pI5.21
Net charge at pH 7.4-1.06
GRAVY-0.932
Hydrophobic fraction0.3333
Extinction coefficient (A280)0
Cys count0

Developability warnings

  • Isomerisation @39 DG — Asp isomerisation — can cost binding
  • Oxidation @1 M — Met oxidation