DEMO-PDL1-020 Design data

Sequence 60 aa

    1  MAEELRRLSE LAKKLLESAK PDGSAESLKK LLEEAKKLLS EFKPDGSAEE LKELLEAAAK

Properties

Molecular weight6611.65
Theoretical pI4.87
Net charge at pH 7.4-2.06
GRAVY-0.592
Hydrophobic fraction0.4
Extinction coefficient (A280)0
Cys count0

Developability warnings

  • Isomerisation @22 DG — Asp isomerisation — can cost binding
  • Isomerisation @45 DG — Asp isomerisation — can cost binding
  • Oxidation @1 M — Met oxidation