DEMO-PDL1-021 Design data

Sequence 55 aa

    1  MAVRLKKLLE EKKKLLFEAK GSGSAQELKK LLEEAKKALG SGSAELLKKL IEEWS

Properties

Molecular weight6127.32
Theoretical pI10.33
Net charge at pH 7.43.94
GRAVY-0.418
Hydrophobic fraction0.4182
Extinction coefficient (A280)5500
Cys count0

Developability warnings

  • Oxidation @1 M — Met oxidation
  • Oxidation @54 W — Trp oxidation — can drive aggregation