PD-L1
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PDL1-R1
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Design
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DEMO-PDL1-022
DEMO-PDL1-022 Design data
This design is an imported data row — not yet a wiki page. There is no body, history, or backlinks, but you can sort and filter it quickly in the table.
Demo data — The sequence and metrics are synthetic values for on-screen demos. Not a real design result.
Sequence 57 aa
1 MAEELRKLNE EVVKLSGGPA EELKRLLEEA KMLLERAQGN GTMEQLKKLL EEYNKLL
Properties
Molecular weight 6555.67 Theoretical pI 4.81 Net charge at pH 7.4 -2.06 GRAVY -0.625 Hydrophobic fraction 0.4035 Extinction coefficient (A280) 1490 Cys count 0
Developability warnings
Deamidation @40 NG — Asn deamidation — charge variant on storageOxidation @1 M — Met oxidationOxidation @32 M — Met oxidationOxidation @43 M — Met oxidationN-glycan sequon @40 NGT — 진핵 발현 시 당사슬이 붙는다 — 대장균이면 무해
Metrics
plddt_complex 0.6934 plddt_binder 0.7321 i_ptm 0.4056 ptm 0.7554 i_pae_norm 0.3985 pae_interaction 19.6858 hbonds_interface 0 unsat_hbonds 1 binder_surface_hydrophobicity 0.4091 binder_rmsd 5.8983 ddg -26.7 sasa_buried 1062 shape_complementarity 0.5808
Filters
bindcraft_default v1
Fail (1/8)
rfdiff_af2ig v1
Fail (0/2)