PD-1/PD-L1 blockade reporter assay for DEMO-PDL1-003.
Binding ≠ potency. Binding off the functional face doesn't block signaling even with a good KD — which is why the stage C epitope choice matters.
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PD-1/PD-L1 blockade reporter assay for DEMO-PDL1-003.
Binding ≠ potency. Binding off the functional face doesn't block signaling even with a good KD — which is why the stage C epitope choice matters.